危重症多发性神经病和肌病与轴索型吉兰最近一周新闻-巴雷综合征很难鉴别，这些疾病均以周围神经损伤（脱髓鞘或轴突变性）为主要病理改变。在这些疾病中，周围神经的损伤是潜在可逆性的。尽早明确诊断并针对性的用药有助于患者的康复。临床医生对危重症多发性神经病和肌病的认识较少，往往将其误诊为吉兰-巴雷综合征。中国吉林大学白求恩第一医院张洪亮教授带领的团队对危重症多发性神经病和肌病进行综述，详细介绍了危重症多发性神经病和肌病的病因、发病机制、临床表现、辅助检查和手段，并突出强调了危重症多发性神经病和肌病与吉兰-巴雷综合征的鉴别诊断要点，对认识危重症多发性神经病和肌病的本质有较好的帮助，从而有助于临床医生及时诊断和危重症多发性神经病和肌病，有助于开展对损伤的周围神经的保护性干预并促进其再生。相关文章发表于《中国神经再生研究（英文版）》杂志2014年1月第1期。
Article: "Critical illness polyneuropathy and myopathy: a systematic review " by Chunkui Zhou1, 2, Limin Wu1, 3, Fengming Ni4, Wei Ji5, Jiang Wu1, Hongliang Zhang1 (1 Department of Neurology, the First Bethune Hospital, Jilin University, Changchun 130021, J
ilin Province, China; 2 Department of Neurology, the Second Part, the First Bethune Hospital, Jilin University, Changchun 130021, Jilin Province, China; 3 Neuroprotection Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Charlestown 02129, MA, USA; 4 Department of Radiotherapy, Oncology Center, the First Bethune Hospital, Jilin University, Changchun 130021, Jilin Province, China; 5 Department of Vascular Surgery, People’s Hospital of Jilin Province, Changchun 130000, Jilin Province, China)
Zhou CK, Wu LM, Ni FM, Ji W, Wu J, Zhang HL. Critical illness polyneuropathy and myopathy: a systematic review. Neural Regen Res. 2014;9(1):101-110.
Critical illness polyneuropathy and myopathy: nerve injury and regeneration
Critical illness polyneuropathy and critical illness myopathy are frequent complications of severe illness that involve sensorimotor axons and skeletal muscles, respectively. Differentiating critical illness polyneuropathy from Guillain-Barré syndrome, especially the axonal variants, may be difficult on purely clinical grounds, as Guillain-Barré syndrome is
known for its variable atypical manifestations. Prof. Hongliang Zhang and team from the First Bethune Hospital, Jilin University in China provide the latest knowledge concerning the pathophysiology of critical illness polyneuropathy/myopathy along with relevant clinical, diagnostic, differentiating, and treatment information for this debilitating neurological disease, and underscores the importance of differentiating critical illness polyneuropathy and myopathy from Guillain-Barré syndrome. The relevant paper was published in the Neural Regeneration Research (Vol. 9, No. 1, 2014).
Article: "Critical illness polyneuropathy and myopathy: a systematic review " by Chunkui Zhou1, 2, Limin Wu1, 3, Fengming Ni4, Wei Ji5, Jiang Wu1, Hongliang Zhang1 (1 Department of Neurology, the First Bethune Hospital, Jilin University, Changchun 130021, Jilin Province, China; 2 Department of Neurology, the Second Part, the First Bethune Hospital, Jilin University, Changchun 130021, Jilin Province, China; 3 Neuroprotection Research Laboratory, Massachusetts General Hospital, Harvard Medical School, Charlestown 02129, MA, USA; 4 Department of Radiotherapy, Oncology Center, the First Bethune Hospital, Jilin University, Changchun 130021, Jilin Province, China; 5 D
epartment of Vascular Surgery, People’s Hospital of Jilin Province, Changchun 130000, Jilin Province, China)
Zhou CK, Wu LM, Ni FM, Ji W, Wu J, Zhang HL. Critical illness polyneuropathy and myopathy: a systematic review. Neural Regen Res. 2014;9(1):101-110.
更多信息 Neural Regeneration Research
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